BioESS60 is available in two concentrations:

• RegularRegular: ~80 mg ESS60/ 100 ml (or 4 mg per teaspoon); stirred for at least two weeks

• Concentrated: ~160 mg ESS60/ 100 ml (or 8 mg per teaspoon); stirred for at least four weeks

Carbon 60, also known as C60, is quickly becoming one of the molecules in the world to optimize mitochondrial health and function, which is why it is one of the pillars in The Mitochondrial Triad. It is a super-antioxidant that mops up free radicals and powerfully quells oxidative stress, both of which play major roles in aging. It has been shown to have ~ 125 - 175x the antioxidant capacity when compared to vitamin C. 

ESS60 is the pharmaceutical grade version of C60. Whereas C60 is utilized for industrial purposes, ESS60 is produced for human consumption. 

ESS60 really came into the limelight with the scientific study that was done on rats that demonstrated those rats that consumed ESS60 combined into olive oil lived 90% longer than their counterparts that drank water (and had all other controlled variables the same). Not only that, when rats die they are commonly riddled with tumors. However, those rats that consumed the olive oil + ESS60 not only lived almost 2x longer, they had no tumors on their body when they died!

Top potential benefits of ESS60:

• Powerful antioxidant 

• Improved mitochondrial function >> boosted energy levels

• Longevity & anti-aging effects

• Anti-inflammatory

• Better sleep

• Joint and pain relief

• Neuroprotective

• Boosted cognitive function

• Cardioprotective

• Detox and liver health

• Potential cancer-protective effects

• Boosted immune function

• Protection against non-ionizing and ionizing radiation (i.e., UV radiation from sun; non-native EMFs from wifi, Bluetooth, 5G, cell towers, etc.)

• Tissue regeneration and wound healing

• Potential antiviral properties

• Improved skin health (yes, this is the C60 we've been using in our Longevv creme for years!)

• Enhanced hair health

BioESS60 is our frequency-enhanced version of ESS60 (which is the highest quality of C60 for human consumption in the world; 99.99% ultra-high purity and solvent free) that is mixed in olive oil and astaxanthin oil. Per BioLight's unparalleled standard for quality products and supplements, both the olive oil and astaxanthin oil are also the highest-quality ingredients in the world (further discussed below). 

BioESS60 is made in small batches and stirred for at least 2 - 4 weeks (based on the concentration outlined above) to ensure optimal suspension of the ESS60 in the oils. To further optimize the potency and effect of the ESS60, we utilize 432 Hz frequency for 9+ hours both before the ESS60 powder is added to the oil and to the entire batch of BioESS60 as the stirring nears its end. With ESS60's incredibly small size and being able to get inside all cells and even into the mitochondria, the implications of this healing frequency may permeate all of the cells in your body.

The potential benefits of enhancing the ESS60 powder with the 432 Hz frequency is to help reduce stress, increase concentration, promote deep states of relaxation and support all healing processes. Additionally, the vibrations of 432 Hz frequency can stimulate the release of endorphins, the body's natural "feel-good" chemicals. These endorphins can help reduce pain, boost the immune system, and enhance overall well-being.

Also, with ESS60's geometric shape and hollow structure, it acts as a carrier of other molecules and substances. This makes ESS60 an amazing conduit to help drive astaxanthin deeper into your body and cells than it otherwise would be able to!

Why is this important? Astaxanthin has been shown to be a powerful antioxidant, amazing for eye health, promotes supple skin, is heart healthy, supports liver health, boosts the immune system, is a brain health super-nutrient and protects metabolic health. Whereas a typical astaxanthin supplement can reach and help some cells, it can now penetrate and benefit virtually all cells in the body when combined with ESS60.

Quality of ingredients in BioESS60

• ESS60: essentially pharmaceutical grade carbon 60; 99.99% ultra-high purity and solvent free, from the most reputable producer of ESS60 in the world.

• Olive oil: we worked tremendously hard to source some the highest-quality olive oil in the world. It is IGP Toscano organic extra virgin olive oil. From a small farm in Tuscany, Italy, the olives are cold pressed within six hours of being picked by hand. The olives are harvested from Frantoio, Moraiolo, Leccino, and Pendolino olive trees. 

• Astaxanthin: from Haematococcus pluvialis algae extract. Cultivated in a hygienic controlled closed system, which allows no contamination and no pollutants. Quality and purity of the product are beyond comparison with outdoor closed or open-grown astaxanthin. Non-GMO. Ideal for vegetarians and shellfish allergy consumers.

Our mastic gum droplets are small and hard, which makes them a favorite for working out your jaw and facial muscles.

Our mastic gum nuggets are soft and easy to chew, with a mild pine flavor. Perfect for dental health and pre- and post-meal digestive bliss.

Wild Cherry Bark Cough Syrup Kit – your natural remedy for soothing relief. Crafted with care, this kit promotes healing from the inside out. Immerse yourself in the delicious blend of natural ingredients, carefully selected for their effectiveness. A safe and reliable solution suitable for all ages, providing comfort without compromise. Say goodbye to cough concerns with this thoughtfully curated kit designed to support your well-being.

The Wild Cherry Bark Syrup Kit is an herbal syrup "must-have" for your medicine cabinet, especially during the colder months.

A full-size bag makes approx. 32 oz, or over 90 single servings. 

Wild Cherry Bark – Traditionally used to help ease discomfort in the throat, wild cherry bark provides a mild, soothing effect.
Black Elderberries – Packed with antioxidants, elderberries are known for supporting overall wellness, especially during seasonal changes.
Licorice Root – Naturally sweet, licorice root is known for its ability to soothe the throat and support respiratory comfort.
Dried Orange – Rich in vitamin C and a touch of natural sweetness, dried orange adds a boost to the body’s defenses and enhances the flavor.
Ginger – Warming and comforting, ginger is well-loved for its ability to promote ease in both the throat and digestive system.
Echinacea – Traditionally used to support the immune system, echinacea is a go-to herb for seasonal wellness.

Mullein – Known for supporting the respiratory system, mullein helps to clear and comfort the lungs.
Rosehips – A natural source of vitamin C, rosehips offer antioxidant support and enhance overall wellness.
Ceylon Cinnamon – This fragrant spice not only adds warmth and flavor but also supports a healthy immune response.

Want to know more about the Wild Cherry Bark Cough Syrup Kit?

CLICK HERE

The Original Elderberry Syrup Kit – DIY Traditional Spice Blend

Make your own rich, spiced elderberry syrup at home with this classic, easy-to-use kit. Featuring whole dried black elderberries and warming botanicals like ginger, cloves, and cinnamon, this small-batch blend is the same recipe passed down through generations of my family.

All you have to do is add the contents to water, simmer gently, strain, and sweeten with your preferred sweetener — honey, maple syrup, or none at all! This kit yields about 20 oz of bold, delicious elderberry syrup that tastes like the holidays in a bottle.

Whether you’re building your home apothecary or just want a fun, hands-on kitchen ritual, this kit makes it easy to keep seasonal wellness traditions alive in your own way.

Ingredients:
Black Elderberries, Rosehips, Ginger, Dried Lemon, Ceylon Cinnamon Stick, Cloves

What You’ll Need at Home:

• 3½ cups water

• Your sweetener of choice (honey, maple syrup, etc.)

• Small pot, strainer, and clean glass jar for storage

Instructions:

1. Add entire contents of the kit to 3½ cups of water

2. Simmer gently for 30–45 minutes

3. Let cool slightly, strain, and discard solids

4. Stir in sweetener to taste

5. Store syrup in a glass jar in the fridge (lasts 2–3 months refrigerated)

A Family Tradition:
This recipe has been used by my family for generations. I was raised in the mountains, learning how to harvest herbs, wildcraft plants, and lean on nature's rhythms for everyday support. Now, I’m honored to pass that tradition on through this kit.

Key Features:

• Makes approx. 20 oz of syrup

• Traditional recipe with warming spice

• No preservatives or fillers

• Naturally caffeine-free

• Exclusive to The Natural Mama Co.

• Vegan-friendly and gluten-free

Propolis Extract – Natural Immune Support & Antioxidant Powerhouse

Unlock the health-enhancing properties of Propolis Extract, a time-honored natural remedy derived from bee propolis. Packed with powerful antioxidants, amino acids, vitamins, and essential minerals, this extract is an all-in-one solution for boosting overall wellness. Whether you’re looking to strengthen your immune system, reduce inflammation, or support skin health, Propolis Extract delivers impressive results.

Key Benefits of Propolis Extract:

• Boosts Immune System: Rich in natural compounds that enhance your body's defense mechanisms, promoting a stronger immune response.
• Reduces Inflammation: Helps soothe and reduce inflammation, supporting joint health and overall comfort.
• Supports Skin Health: Known for its skin-soothing properties, it aids in the healing process, making it beneficial for common skin issues and irritations.

Made with simple, clean ingredients—just bee propolis and non-GMO vegetable glycerin—our Propolis Extract is pure, potent, and free of unnecessary additives. It’s crafted in small batches to preserve its powerful medicinal qualities, ensuring that every drop delivers maximum effectiveness.

Why Choose Our Propolis Extract?

• 100% natural ingredients
• Made with non-GMO vegetable glycerin
• Handmade in small batches for unmatched quality
• Vegan and gluten-free

Incorporate Propolis Extract into your daily wellness routine for a natural boost that supports your body from the inside out. Perfect for anyone seeking a reliable, time-tested remedy to enhance immune function, fight inflammation, and maintain healthy skin.

Organic Elderberry Syrup – Personal Sized 16 oz Bottle

Our signature elderberry syrup is a flavorful blend of organic botanicals and wildflower honey, handcrafted to bring traditional herbal wisdom into your daily routine. Made with whole dried elderberries and warming spices like ginger, clove, and cinnamon, this small-batch syrup is as rich in taste as it is in plant-based goodness.

Naturally sweetened with raw wildflower honey and free of refined sugar, it’s a delicious way to enjoy the deep, earthy flavor of elderberries — perfect for the whole family.

Whether stirred into tea, drizzled over pancakes, or enjoyed by the spoonful, this 16 oz bottle makes it easy to keep your kitchen stocked with nature’s favorite berry blend.

What Makes It Special:

• Made from whole dried elderberries and organic herbs

• Naturally sweetened with raw wildflower honey

• No refined sugar, additives, or artificial flavors

• Cold-processed to preserve the integrity of each ingredient

• Small-batch made by The Natural Mama Co.

Ingredients:
Spring Water, Dried Black Elderberries, Ceylon Cinnamon, Cloves, Rose Petals, Dried Lemon, Lemon Juice, Ginger, Rose Hips, Raw Wildflower Honey.

Storage Instructions:
Unopened: shelf-stable for up to 1 year.
Opened: refrigerate and enjoy within 3–4 months.

Key Features:

• Organic ingredients

• Gluten-free, dairy-free

• Naturally sweetened
  

• Handmade in small batches

• Exclusive to The Natural Mama Co.

Elderberry Syrup Kit - Hibiscus & Rose

The Hibiscus & Rose is a blend of herbs and spices a little differently than you will find anywhere else. It has the full-bodied flavor of black elderberries complimented with traditional spices. I then softened the flavor of the traditional elderberry syrup by adding in rosehips and rose petals. 

This easy to make DIY kit will give you about 20oz of insanely delicious Elderberry Syrup! 
All you need to do is add the kit to water, simmer, strain, and sweeten with the sweetener of YOUR choice. You'll find that the Hibiscus and Rose kit has a much softer flavor than my Original kit, but don't' worry, it has all the same spices. 

Elderberries 

Rose Hips 

Ginger 

Cloves 

Ceylon Cinnamon 

Dried Lemon 

Hibiscus 

Rose Petals  


Kits are shelf-stable for 2-3 years if stored in a cool dark cabinet. 

Elderberry Drops

Elderberry drops offer the benfits of black elderberry, mullein, and orange. They are great for the mom or family on the go as they do not require refrigeration. Can be used daily, and it is easily hidden in any liquid or food for those picky eaters! Elderberry drops come in a 2-ounce bottle and offer 90+ adult-size servings.

INGREDIENTS: Black Elderberry, Mullein, Orange, Filtered Water, non-GMO vegetable glycerin.

DOES NOT CONTAIN

Dairy, Gluten, Peanuts, Shellfish, Soy, Sugar, Tree Nuts, Yeast.

*Statement of transparency: the price of BioBlue Leuco is simply a reflection of the fact that sourcing the ultra-high purity pharmaceutical-grade leucomethylene blue is twice as expensive as sourcing the ultra-high purity pharmaceutical-grade methylene blue. Otherwise, all ingredients are exactly the same between the two formulas.

BioBlue Leuco is the first supplement of its kind with the incorporation of the groundbreaking mitochondrial-boosting molecule, leucomethylene blue!

Methylene blue is quickly becoming a darling supplement in the health, wellness, longevity and biohacking worlds due to its many health benefits, highlighted by boosting both mitochondrial function and brain health.

However, the lesser known molecule, leucomethylene blue (leucoMB), seems to have some advantages over methylene blue (MB). For starters, leucoMB is the reduced and stabilized form of MB, meaning it has gained an electron and is much more efficient for our bodies to process. When ingesting MB, your body converts into leucoMB; therefore, by ingesting leucoMB you circumvent this metabolic process. This provides the following advantages to leucoMB:

• Higher bioabsorption = increased bioavailability

• Quicker cognitive & antioxidant effect

• With MB already being an electron donor, leucoMB has even more electrons to donate; more electrons equals more energy production in the mitochondria! 

• Easier for the body to process; this is particularly important for those with liver and/or kidney issues. (LeucoMB can work where MB cannot because the body cannot process the MB and convert it to leucoMB internally)

• Lower toxicity (even ultra pure, pharmaceutical compounds, when reduced, will further remove any metals, impurities that may be left; this is an inherent result of reducing anything)

Neurofilament light chain (NfL) is an established biomarker for brain neurodegeneration. Increased concentrations NfL are known to correlate with tau pathology, disease severity, and therefore cognitive decline and brain atrophy in Alzheimer's disease. A recently published study demonstrated that taking 16 mg/day of leucoMB reduced NfL concentration in blood by 93%! 

It is worth noting that leucoMB has a much less intense blue color compared to MB. This means that leucoMB stains your teeth, tongue, etc. significantly less than MB — for some people, this is very desirable and advantageous:

• Those wanting to use MB at work, at the gym, on an airplane, when out in other social situations, etc.

• Those wanting to use MB for their pets (they have mitochondria too!)

However, the color of MB is blue due to the fact that the phenothiazinium molecule absorbs visible light strongly in the region of 600–700 nm (red light). In its reduced form (leucoMB), it is colorless and does not absorb light in the visible region. As you will see in the BioBlue Leuco supplement, it is surely not colorless, but rather a muted blue color compared to MB. With that being said, BioBlue Leuco likely has a lower photodynamic capacity compared to BioBlue, which contains MB.

Ultimately, BioBlue Leuco is a supreme methylene blue product that works as a standalone cellular energizer via boosting mitochondrial health or as an incredibly powerful red light therapy synergist that can be added to any RLT treatment. This is because of the unique blend of ingredients that have been incorporated with the pharmaceutical grade (USP >99.5%) leucomethylene blue at 1% solution.

Top 10 benefits of methylene blue*:

1. Boosting brain health/cognition

2. Anti-malarial

3. Anti-viral

4. Reduce depression

5. Mitigate/reverse dementia

6. Autism

7. Pain relief

8. Heart health

9. Cancer

10. Chemical poisoning and overdose

Learn more about methylene blue by clicking here

BioBlue Leuco ingredients:

Triple distilled biophotonic structured water - not only is the water we utilize clean, purified and distilled, but its energy has been enhanced via direct sunlight in Miron violetglass jars and has been structured, which further upgrades its energy and helps better absorb nutrients.

Leucomethylene blue USP Grade (>99.5%), 1% solution, cGMP manufactured - only the most pure and highest-quality pharmaceutical grade methylene blue is used in BioBlue. Here are a list of some of the health benefits of methylene blue:

• Anti-viral, anti-malarial

• Major brain-boosting properties

• Reduce anxiety, depression, dementia

• Improve overall brain function, cognition, energy, attention/focus and emotional regulation

• Restores mitochondrial health and function by improving oxidative metabolism

• Selectively targets cells that need the most healing first before others

• Cancer cells are targeted first due to their inefficient energy production (which is what methylene blue targets first)

Nicotinamide mononucleotide (NMN) - highly touted by Dr. David Sinclair in his New York Times bestseller, Lifespan, this molecule is a NAD+ precursor that has become wildly popular due to its ability to increase energy and boost mitochondrial health. As we age, our NAD+ levels naturally decline and, thus, NMN can play a vital role in mitigating that decline in energy production in the mitochondria.

Colloidal gold - Produced by electrolysis that insures highest quality, homogeneity and stability. This method results in a high-quality and well-dispersed colloidal gold product with the highest zeta potential (a high zeta potential indicates that the particles have a strong electrical charge). On top of improving cognitive function, colloidal gold offers additional benefits, such as reducing inflammation, boosting the immune system, reducing aging and improving skin and hair health.

Colloidal silver - notorious for its anti-microbial properties and commonly used for wound care and skin health, colloidal silver also provides anti-inflammatory benefits, strong immune support and has some potential for respiratory support.

Fulvic acid -  known to raise the voltage of your cells, we added the purest fulvic acid in order to enhance the absorption of the ingredients. This means that the methylene blue and NMN may be taken up and better utilized by your cells and tissues. Fulvic acid has other beneficial properties, such as being a powerful antioxidant, anti-inflammatory and promotes improved gut and skin health.

BioBlue Leuco is packaged in a Miron violetglass. Miron glass elevates the frequency of enclosed water and nutrients by selectively harnessing beneficial sunlight wavelengths, enhancing their bioavailability and vitality for a more profound and resonant impact on the body.

Recommended Dosing**:

Contraindications & Precautions for Methylene Blue

Contraindications:

1. G6PD Deficiency: Methylene blue is contraindicated in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency, a genetic enzyme disorder. Using methylene blue in individuals with this condition can lead to hemolytic anemia, a potentially severe breakdown of red blood cells.

2. Sulfite Sensitivity: Some methylene blue formulations may contain sulfites, which can trigger allergic reactions in individuals with sulfite sensitivity or allergies.

Precautions:

1. Renal Impairment: Patients with kidney disease or impaired renal function should be monitored carefully when using methylene blue. Dosing adjustments may be necessary due to changes in drug elimination.

2. Hepatic Impairment: Individuals with liver disease or impaired liver function should also be monitored closely, as methylene blue is metabolized by the liver.

3. Pregnancy and Breastfeeding: The safety of methylene blue during pregnancy and breastfeeding is not well established. It should be used with caution in pregnant or nursing women, with careful consideration of the potential risks and benefits.

4. Hypotension: Methylene blue can lower blood pressure. Patients with hypotension (low blood pressure) should be monitored closely, and adjustments to the dosage may be needed.

5. Medication Interactions: Methylene blue may interact with various medications, including serotonergic agents (e.g., certain antidepressants) and monoamine oxidase inhibitors (MAOIs). These interactions can lead to potentially dangerous serotonin syndrome. Inform your healthcare provider about all medications you are taking.

6. Allergies: Individuals with known allergies to methylene blue or other dyes should avoid its use.

7. Oxidative Stress: Methylene blue has antioxidant properties. In conditions where oxidative stress is not a factor, such as in some cancers, its use may not be advisable.

8. Children: While methylene blue is generally considered safe for children when used as a dye for diagnostic purposes, its use as a medication should be under the supervision of a healthcare professional and carefully considered in pediatric patients.

*As outlined in Mark Sloan's book, The Ultimate Guide to Methylene Blue

**These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Information provided by this website or this company is not a substitute for individual medical advice. | ©BioLight, Inc, 2023

Methylene blue is quickly becoming a prized supplement in the health, wellness, longevity and biohacking worlds due to its many health benefits, highlighted by boosting both mitochondrial function and brain health.

To make matters even more advantageous, methylene blue possesses photodynamic capacity that makes it a major synergist with photobiomodulaton; essentially, methylene blue amplifies the benefits of red light therapy.

Ultimately, BioBlue is a supreme methylene blue product that works as a standalone cellular energizer via boosting mitochondrial health or as an incredibly powerful red light therapy synergist that can be added to any RLT treatment. This is because of the unique blend of ingredients that have been incorporated with the pharmaceutical grade (USP >99.5%) methylene blue at 1% solution.

Top 10 benefits of methylene blue*:

1. Boosting brain health/cognition

2. Anti-malarial

3. Anti-viral

4. Reduce depression

5. Mitigate/reverse dementia

6. Autism

7. Pain relief

8. Heart health

9. Cancer

10. Chemical poisoning and overdose

Learn more about methylene blue by clicking here

BioBlue ingredients:

Triple distilled biophotonic structured water - not only is the water we utilize clean, purified and distilled, but its energy has been enhanced via direct sunlight in Miron violetglass jars and has been structured, which further upgrades its energy and helps better absorb nutrients.

Methylene blue USP Grade (>99.5%), 1% solution, cGMP manufactured - only the most pure and highest-quality pharmaceutical grade methylene blue is used in BioBlue. Here are a list of some of the health benefits of methylene blue:

• Anti-viral, anti-malarial

• Major brain-boosting properties

• Reduce anxiety, depression, dementia

• Improve overall brain function, cognition, energy, attention/focus and emotional regulation

• Restores mitochondrial health and function by improving oxidative metabolism

• Selectively targets cells that need the most healing first before others

• Cancer cells are targeted first due to their inefficient energy production (which is what methylene blue targets first)

Nicotinamide mononucleotide (NMN) - highly touted by Dr. David Sinclair in his New York Times bestseller, Lifespan, this molecule is a NAD+ precursor that has become wildly popular due to its ability to increase energy and boost mitochondrial health. As we age, our NAD+ levels naturally decline and, thus, NMN can play a vital role in mitigating that decline in energy production in the mitochondria.

Colloidal gold - Produced by electrolysis that insures highest quality, homogeneity and stability. This method results in a high-quality and well-dispersed colloidal gold product with the highest zeta potential (a high zeta potential indicates that the particles have a strong electrical charge). On top of improving cognitive function, colloidal gold offers additional benefits, such as reducing inflammation, boosting the immune system, reducing aging and improving skin and hair health.

Colloidal silver - notorious for its anti-microbial properties and commonly used for wound care and skin health, colloidal silver also provides anti-inflammatory benefits, strong immune support and has some potential for respiratory support.

Fulvic acid -  known to raise the voltage of your cells, we added the purest fulvic acid in order to enhance the absorption of the ingredients. This means that the methylene blue and NMN may be taken up and better utilized by your cells and tissues. Fulvic acid has other beneficial properties, such as being a powerful antioxidant, anti-inflammatory and promotes improved gut and skin health.

BioBlue is packaged in a Miron violetglass. Miron glass elevates the frequency of enclosed water and nutrients by selectively harnessing beneficial sunlight wavelengths, enhancing their bioavailability and vitality for a more profound and resonant impact on the body.

Recommended Dosing**:

Contraindications & Precautions for Methylene Blue

Contraindications:

1. G6PD Deficiency: Methylene blue is contraindicated in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency, a genetic enzyme disorder. Using methylene blue in individuals with this condition can lead to hemolytic anemia, a potentially severe breakdown of red blood cells.

2. Sulfite Sensitivity: Some methylene blue formulations may contain sulfites, which can trigger allergic reactions in individuals with sulfite sensitivity or allergies.

Precautions:

1. Renal Impairment: Patients with kidney disease or impaired renal function should be monitored carefully when using methylene blue. Dosing adjustments may be necessary due to changes in drug elimination.

2. Hepatic Impairment: Individuals with liver disease or impaired liver function should also be monitored closely, as methylene blue is metabolized by the liver.

3. Pregnancy and Breastfeeding: The safety of methylene blue during pregnancy and breastfeeding is not well established. It should be used with caution in pregnant or nursing women, with careful consideration of the potential risks and benefits.

4. Hypotension: Methylene blue can lower blood pressure. Patients with hypotension (low blood pressure) should be monitored closely, and adjustments to the dosage may be needed.

5. Medication Interactions: Methylene blue may interact with various medications, including serotonergic agents (e.g., certain antidepressants) and monoamine oxidase inhibitors (MAOIs). These interactions can lead to potentially dangerous serotonin syndrome. Inform your healthcare provider about all medications you are taking.

6. Allergies: Individuals with known allergies to methylene blue or other dyes should avoid its use.

7. Oxidative Stress: Methylene blue has antioxidant properties. In conditions where oxidative stress is not a factor, such as in some cancers, its use may not be advisable.

8. Children: While methylene blue is generally considered safe for children when used as a dye for diagnostic purposes, its use as a medication should be under the supervision of a healthcare professional and carefully considered in pediatric patients.

*As outlined in Mark Sloan's book, The Ultimate Guide to Methylene Blue

**These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Information provided by this website or this company is not a substitute for individual medical advice. | ©BioLight, Inc, 2023

BioBlue Leuco Capsules are the first encapsulated methylene blue supplement on the market!

With BioBlue Leuco Capsules, you no longer have to worry about stained teeth/tongue, clothes, countertops, luggage bags, etc. Not a fan of the "flavor" of leucomethylene blue? That is now a memory of the past!

This supplement combines two of the most potent molecules to safely and effectively boost mitochondrial function: leucomethylene blue and taurine. Learn about the profound benefits of both ingredients below.

Methylene blue is quickly becoming a popular supplement in the wellness, longevity and mitochondrial-centric audiences. The lesser known molecule, leucomethylene blue (leucoMB), seems to have some advantages over methylene blue (MB). For starters, leucoMB is the reduced and stabilized form of MB, meaning it has gained an electron and is much more efficient for our bodies to process. When ingesting MB, your body converts into leucoMB; therefore, by ingesting leucoMB you circumvent this metabolic process. This provides the following advantages to leucoMB:

• Higher bioabsorption = increased bioavailability

• Quicker cognitive & antioxidant effect

• With MB already being an electron donor, leucoMB has even more electrons to donate; more electrons equals more energy production in the mitochondria! 

• Easier for the body to process; this is particularly important for those with liver and/or kidney issues. (LeucoMB can work where MB cannot because the body cannot process the MB and convert it to leucoMB internally)

• Lower toxicity (even ultra pure, pharmaceutical compounds, when reduced, will further remove any metals, impurities that may be left; this is an inherent result of reducing anything)

Neurofilament light chain (NfL) is an established biomarker for brain neurodegeneration. Increased concentrations NfL are known to correlate with tau pathology, disease severity, and therefore cognitive decline and brain atrophy in Alzheimer's disease. A recently published study demonstrated that taking 16 mg/day of leucoMB reduced NfL concentration in blood by 93%! 

BioBlue Leuco Capsules ingredients

• Enhancement of ATP Production - Methylene blue serves as an alternative electron carrier in the mitochondrial electron transport chain (ETC). It can bypass dysfunctional components in the ETC and facilitate electron flow, which increases ATP (energy) production, especially in cells with impaired mitochondrial function.

• Reduction of Reactive Oxygen Species (ROS) - Methylene blue has antioxidant properties and can reduce the production of reactive oxygen species (ROS) in mitochondria. Excessive ROS production can damage mitochondrial DNA, lipids, and proteins, leading to cellular dysfunction. MB helps minimize oxidative stress by acting as an electron acceptor.

• Prevention of Mitochondrial Dysfunction - By improving the efficiency of the electron transport chain and reducing oxidative stress, methylene blue helps prevent mitochondrial dysfunction. This is important for maintaining cellular energy levels, especially in tissues with high energy demands like the brain and heart.

• Protection Against Mitochondrial Damage - Methylene blue helps protect mitochondria from damage caused by toxins, ischemia (restricted blood flow), and metabolic stress. This is particularly useful in conditions that compromise mitochondrial integrity and function, such as neurodegenerative diseases and aging.

• Improved Cellular Respiration - By facilitating electron transport and improving the efficiency of the respiratory chain, methylene blue can enhance cellular respiration. This increases oxygen consumption in the mitochondria, which supports better metabolic performance and energy utilization.

• Neuroprotective Effects - Methylene blue has demonstrated neuroprotective effects, in part by improving mitochondrial function in neurons. It is being studied for potential benefits in treating neurodegenerative conditions like Alzheimer’s and Parkinson’s diseases, where mitochondrial dysfunction plays a role in disease progression.

• Protection Against Mitochondrial Permeability Transition - Methylene blue can help prevent the opening of the mitochondrial permeability transition pore (mPTP), a channel whose opening leads to mitochondrial swelling, dysfunction, and cell death. By inhibiting mPTP, methylene blue supports the longevity and resilience of mitochondria under stress.

• Promotion of Mitophagy - Methylene blue may also stimulate mitophagy, the process by which damaged or dysfunctional mitochondria are selectively removed. This helps maintain a healthy population of mitochondria within cells, promoting overall cellular vitality and function.

Learn more about methylene blue by clicking here

Taurine

• Prevention of Mitochondrial Dysfunction - Taurine can help prevent mitochondrial dysfunction by reducing oxidative damage, maintaining proper ion balance, and enhancing energy production. Mitochondrial dysfunction is linked to a range of diseases, including neurodegenerative diseases, diabetes, and heart conditions.

• Antioxidant Properties - Taurine acts as a potent antioxidant, reducing oxidative stress in mitochondria. This is important because mitochondria produce reactive oxygen species (ROS) as by-products of energy production, which can damage cells if not properly managed.

• Regulation of Calcium Homeostasis - Taurine helps regulate calcium levels within cells and mitochondria. Proper calcium balance is essential for mitochondrial function, as calcium overload can lead to mitochondrial dysfunction, energy failure, and cell death.

• Improved ATP Production - Taurine enhances mitochondrial efficiency in producing ATP (adenosine triphosphate), the main energy currency of the cell. This is vital for sustaining energy-demanding processes throughout the body, especially in tissues with high energy needs like muscles and the brain.

• Mitochondrial Membrane Stabilization - Taurine contributes to the stability and integrity of the mitochondrial membrane, which is crucial for maintaining the electrochemical gradients needed for ATP synthesis. It also protects against mitochondrial permeability transition, a process that can lead to cell death.

• Anti-Inflammatory Effects - Taurine helps reduce inflammation, which is important for protecting mitochondria from inflammatory damage. Chronic inflammation can impair mitochondrial function and contribute to diseases like cardiovascular and metabolic disorders.

Contraindications & Precautions for Methylene Blue

Contraindications:

1. G6PD Deficiency: Methylene blue is contraindicated in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency, a genetic enzyme disorder. Using methylene blue in individuals with this condition can lead to hemolytic anemia, a potentially severe breakdown of red blood cells.

2. Sulfite Sensitivity: Some methylene blue formulations may contain sulfites, which can trigger allergic reactions in individuals with sulfite sensitivity or allergies.

Precautions:

1. Renal Impairment: Patients with kidney disease or impaired renal function should be monitored carefully when using methylene blue. Dosing adjustments may be necessary due to changes in drug elimination.

2. Hepatic Impairment: Individuals with liver disease or impaired liver function should also be monitored closely, as methylene blue is metabolized by the liver.

3. Pregnancy and Breastfeeding: The safety of methylene blue during pregnancy and breastfeeding is not well established. It should be used with caution in pregnant or nursing women, with careful consideration of the potential risks and benefits.

4. Hypotension: Methylene blue can lower blood pressure. Patients with hypotension (low blood pressure) should be monitored closely, and adjustments to the dosage may be needed.

5. Medication Interactions: Methylene blue may interact with various medications, including serotonergic agents (e.g., certain antidepressants) and monoamine oxidase inhibitors (MAOIs). These interactions can lead to potentially dangerous serotonin syndrome. Inform your healthcare provider about all medications you are taking.

6. Allergies: Individuals with known allergies to methylene blue or other dyes should avoid its use.

7. Oxidative Stress: Methylene blue has antioxidant properties. In conditions where oxidative stress is not a factor, such as in some cancers, its use may not be advisable.

8. Children: While methylene blue is generally considered safe for children when used as a dye for diagnostic purposes, its use as a medication should be under the supervision of a healthcare professional and carefully considered in pediatric patients.

**These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Information provided by this website or this company is not a substitute for individual medical advice. | ©BioLight, Inc, 2023

BioBlue Capsules are the first encapsulated methylene blue supplement on the market!

With BioBlue Capsules, you no longer have to worry about stained teeth/tongue, clothes, countertops, luggage bags, etc. Not a fan of the "flavor" of methylene blue? That is now a memory of the past!

This supplement combines two of the most potent molecules to safely and effectively boost mitochondrial function: methylene blue and taurine. Learn about the profound benefits of both ingredients below.

BioBlue Capsules ingredients

• Enhancement of ATP Production - Methylene blue serves as an alternative electron carrier in the mitochondrial electron transport chain (ETC). It can bypass dysfunctional components in the ETC and facilitate electron flow, which increases ATP (energy) production, especially in cells with impaired mitochondrial function.

• Reduction of Reactive Oxygen Species (ROS) - Methylene blue has antioxidant properties and can reduce the production of reactive oxygen species (ROS) in mitochondria. Excessive ROS production can damage mitochondrial DNA, lipids, and proteins, leading to cellular dysfunction. MB helps minimize oxidative stress by acting as an electron acceptor.

• Prevention of Mitochondrial Dysfunction - By improving the efficiency of the electron transport chain and reducing oxidative stress, methylene blue helps prevent mitochondrial dysfunction. This is important for maintaining cellular energy levels, especially in tissues with high energy demands like the brain and heart.

• Protection Against Mitochondrial Damage - Methylene blue helps protect mitochondria from damage caused by toxins, ischemia (restricted blood flow), and metabolic stress. This is particularly useful in conditions that compromise mitochondrial integrity and function, such as neurodegenerative diseases and aging.

• Improved Cellular Respiration - By facilitating electron transport and improving the efficiency of the respiratory chain, methylene blue can enhance cellular respiration. This increases oxygen consumption in the mitochondria, which supports better metabolic performance and energy utilization.

• Neuroprotective Effects - Methylene blue has demonstrated neuroprotective effects, in part by improving mitochondrial function in neurons. It is being studied for potential benefits in treating neurodegenerative conditions like Alzheimer’s and Parkinson’s diseases, where mitochondrial dysfunction plays a role in disease progression.

• Protection Against Mitochondrial Permeability Transition - Methylene blue can help prevent the opening of the mitochondrial permeability transition pore (mPTP), a channel whose opening leads to mitochondrial swelling, dysfunction, and cell death. By inhibiting mPTP, methylene blue supports the longevity and resilience of mitochondria under stress.

• Promotion of Mitophagy - Methylene blue may also stimulate mitophagy, the process by which damaged or dysfunctional mitochondria are selectively removed. This helps maintain a healthy population of mitochondria within cells, promoting overall cellular vitality and function.

Learn more about methylene blue by clicking here

Taurine

• Prevention of Mitochondrial Dysfunction - Taurine can help prevent mitochondrial dysfunction by reducing oxidative damage, maintaining proper ion balance, and enhancing energy production. Mitochondrial dysfunction is linked to a range of diseases, including neurodegenerative diseases, diabetes, and heart conditions.

• Antioxidant Properties - Taurine acts as a potent antioxidant, reducing oxidative stress in mitochondria. This is important because mitochondria produce reactive oxygen species (ROS) as by-products of energy production, which can damage cells if not properly managed.

• Regulation of Calcium Homeostasis - Taurine helps regulate calcium levels within cells and mitochondria. Proper calcium balance is essential for mitochondrial function, as calcium overload can lead to mitochondrial dysfunction, energy failure, and cell death.

• Improved ATP Production - Taurine enhances mitochondrial efficiency in producing ATP (adenosine triphosphate), the main energy currency of the cell. This is vital for sustaining energy-demanding processes throughout the body, especially in tissues with high energy needs like muscles and the brain.

• Mitochondrial Membrane Stabilization - Taurine contributes to the stability and integrity of the mitochondrial membrane, which is crucial for maintaining the electrochemical gradients needed for ATP synthesis. It also protects against mitochondrial permeability transition, a process that can lead to cell death.

• Anti-Inflammatory Effects - Taurine helps reduce inflammation, which is important for protecting mitochondria from inflammatory damage. Chronic inflammation can impair mitochondrial function and contribute to diseases like cardiovascular and metabolic disorders.

Contraindications & Precautions for Methylene Blue

Contraindications:

1. G6PD Deficiency: Methylene blue is contraindicated in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency, a genetic enzyme disorder. Using methylene blue in individuals with this condition can lead to hemolytic anemia, a potentially severe breakdown of red blood cells.

2. Sulfite Sensitivity: Some methylene blue formulations may contain sulfites, which can trigger allergic reactions in individuals with sulfite sensitivity or allergies.

Precautions:

1. Renal Impairment: Patients with kidney disease or impaired renal function should be monitored carefully when using methylene blue. Dosing adjustments may be necessary due to changes in drug elimination.

2. Hepatic Impairment: Individuals with liver disease or impaired liver function should also be monitored closely, as methylene blue is metabolized by the liver.

3. Pregnancy and Breastfeeding: The safety of methylene blue during pregnancy and breastfeeding is not well established. It should be used with caution in pregnant or nursing women, with careful consideration of the potential risks and benefits.

4. Hypotension: Methylene blue can lower blood pressure. Patients with hypotension (low blood pressure) should be monitored closely, and adjustments to the dosage may be needed.

5. Medication Interactions: Methylene blue may interact with various medications, including serotonergic agents (e.g., certain antidepressants) and monoamine oxidase inhibitors (MAOIs). These interactions can lead to potentially dangerous serotonin syndrome. Inform your healthcare provider about all medications you are taking.

6. Allergies: Individuals with known allergies to methylene blue or other dyes should avoid its use.

7. Oxidative Stress: Methylene blue has antioxidant properties. In conditions where oxidative stress is not a factor, such as in some cancers, its use may not be advisable.

8. Children: While methylene blue is generally considered safe for children when used as a dye for diagnostic purposes, its use as a medication should be under the supervision of a healthcare professional and carefully considered in pediatric patients.

**These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Information provided by this website or this company is not a substitute for individual medical advice. | ©BioLight, Inc, 2023

Methylene blue is quickly becoming a highly sought after supplement in the health, wellness, longevity and biohacking worlds due to its many health benefits, highlighted by boosting both mitochondrial function and brain health.

BioBlue Calm is a blend of six herbs and minerals combined with pharmaceutical grade methylene blue (USP >99.5%) to help promote relaxation and a sense of calm. This recipe includes all of the same ingredients as our flagship BioBlue product minus nicotinamide mononucleotide (NMN). We decided to remove NMN because while is not a stimulant, it can be stimulating to our physiology given its properties for improving mitochondrial function and energy production.

Between the removal of the NMN and the addition of:

• Ashwagandha

• Valerian

• Passionflower

• Kava

• Magnesium glycinate

• Magnesium L-threonate

...BioBlue Calm functions as a "weighted blanket" for your brain and your nervous system, providing a physiological tranquility in times of stress, anxiety and/or when falling asleep is difficult.

All of the above herbs and minerals contribute to reducing cortisol levels and improved GABA activity in the brain. This alone promotes a deep sense of calm.

Top 10 benefits of methylene blue*:

1. Boosting brain health/cognition

2. Anti-malarial

3. Anti-viral

4. Reduce depression

5. Mitigate/reverse dementia

6. Autism

7. Pain relief

8. Heart health

9. Cancer

10. Chemical poisoning and overdose

Learn more about methylene blue by clicking here

BioBlue Calm ingredients:

Triple distilled biophotonic structured water - not only is the water we utilize clean, purified and distilled, but its energy has been enhanced via direct sunlight in Miron violetglass jars and has been structured, which further upgrades its energy and helps better absorb nutrients.

Methylene blue USP Grade (>99.5%), 1% solution, cGMP manufactured - only the most pure and highest-quality pharmaceutical grade methylene blue is used in BioBlue. Here are a list of some of the health benefits of methylene blue:

• Anti-viral, anti-malarial

• Major brain-boosting properties

• Reduce anxiety, depression, dementia

• Improve overall brain function, cognition, energy, attention/focus and emotional regulation

• Restores mitochondrial health and function by improving oxidative metabolism

• Selectively targets cells that need the most healing first before others

• Cancer cells are targeted first due to their inefficient energy production (which is what methylene blue targets first)

Ashwaganda root (Withania somnifera)* - Ashwagandha is an adaptogenic herb that has been used for centuries in traditional Ayurvedic medicine to promote relaxation, reduce stress, and improve overall well-being. Ashwagandha helps promote calmness by reducing cortisol levels, enhancing GABA activity in the brain, reducing inflammation and contributing as an antioxidant and neuroprotection. 

Valerian rhizome w/ root (Valeriana officinalis)* - Valerian root has been used for centuries as a natural remedy for promoting relaxation and improving sleep. Valerian helps promote calmness by enhancing GABA activity in the brain, modulating serotonin receptors in the brain, modulating adenosine receptors (which promotes relaxation and sleepiness) and reducing cortisol levels.

Passionflower flowering aerial parts (Passiflora incarnata)* - Passionflower has a long history of use as a natural remedy for promoting relaxation and reducing anxiety. Passionflower helps promote calmness by enhancing GABA activity in the brain, modulating serotonin receptors in the brain, contributing as an antioxidant, reducing cortisol levels and modulating of neurotransmitters, such as dopamine and noradrenaline.

Kava rhizome w/ root (Piper methysticum) - Kava is a plant native to the South Pacific islands, where it has been used for centuries in traditional ceremonies and as a beverage with sedative and anxiolytic (anxiety-reducing) effects. The relaxation-promoting effects of kava are primarily attributed to its bioactive compounds, particularly kavalactones. Kava helps promote calmness by  enhancing GABA activity in the brain, modulating of neurotransmitters (i.e., dopamine and noradrenaline), reducing cortisol levels, relaxing muscles and promoting reduced inflammation and antioxidant activity. 

Magnesium glycinate -  is a form of magnesium that is chelated with glycine, an amino acid. This compound is often used as a dietary supplement to address magnesium deficiency, and it is also known for its calming and relaxation-promoting effects. Magnesium glycinate helps promote calmness by its improved absorption (compared to other forms of magnesium), regulation of neurotransmitters (such as GABA), modulation of the HPA axis (which helps reduce cortisol levels), relaxing muscles, regulation of the nervous system (i.e., reducing excitability), reducing inflammation and promoting restful sleep.

Magnesium L-threonate -  is a form of magnesium that is bonded with L-threonate, a compound derived from vitamin C. This specific formulation is notable for its ability to effectively penetrate the blood-brain barrier, leading to increased magnesium levels in the brain. Magnesium L-threonate helps promote calmness by enhanced GABA activity, modulation of NMDA receptors (i.e., reducing hyperactivity in the brain), protection against excitotoxicity, reducing inflammation and enhancing brain function and synaptic activity.

Colloidal gold - Produced by electrolysis that insures highest quality, homogeneity and stability. This method results in a high-quality and well-dispersed colloidal gold product with the highest zeta potential (a high zeta potential indicates that the particles have a strong electrical charge). On top of improving cognitive function, colloidal gold offers additional benefits, such as reducing inflammation, boosting the immune system, reducing aging and improving skin and hair health.

Colloidal silver - notorious for its anti-microbial properties and commonly used for wound care and skin health, colloidal silver also provides anti-inflammatory benefits, strong immune support and has some potential for respiratory support.

Fulvic acid -  known to raise the voltage of your cells, we added the purest fulvic acid in order to enhance the absorption of the ingredients. This means that the methylene blue and NMN may be taken up and better utilized by your cells and tissues. Fulvic acid has other beneficial properties, such as being a powerful antioxidant, anti-inflammatory and promotes improved gut and skin health.

* = organic ingredient

BioBlue Calm is packaged in a Miron violetglass. Miron glass elevates the frequency of enclosed water and nutrients by selectively harnessing beneficial sunlight wavelengths, enhancing their bioavailability and vitality for a more profound and resonant impact on the body.

Recommended Dosing**:

Contraindications & Precautions for Methylene Blue

Contraindications:

1. G6PD Deficiency: Methylene blue is contraindicated in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency, a genetic enzyme disorder. Using methylene blue in individuals with this condition can lead to hemolytic anemia, a potentially severe breakdown of red blood cells.

2. Sulfite Sensitivity: Some methylene blue formulations may contain sulfites, which can trigger allergic reactions in individuals with sulfite sensitivity or allergies.

Precautions:

1. Renal Impairment: Patients with kidney disease or impaired renal function should be monitored carefully when using methylene blue. Dosing adjustments may be necessary due to changes in drug elimination.

2. Hepatic Impairment: Individuals with liver disease or impaired liver function should also be monitored closely, as methylene blue is metabolized by the liver.

3. Pregnancy and Breastfeeding: The safety of methylene blue during pregnancy and breastfeeding is not well established. It should be used with caution in pregnant or nursing women, with careful consideration of the potential risks and benefits.

4. Hypotension: Methylene blue can lower blood pressure. Patients with hypotension (low blood pressure) should be monitored closely, and adjustments to the dosage may be needed.

5. Medication Interactions: Methylene blue may interact with various medications, including serotonergic agents (e.g., certain antidepressants) and monoamine oxidase inhibitors (MAOIs). These interactions can lead to potentially dangerous serotonin syndrome. Inform your healthcare provider about all medications you are taking.

6. Allergies: Individuals with known allergies to methylene blue or other dyes should avoid its use.

7. Oxidative Stress: Methylene blue has antioxidant properties. In conditions where oxidative stress is not a factor, such as in some cancers, its use may not be advisable.

8. Children: While methylene blue is generally considered safe for children when used as a dye for diagnostic purposes, its use as a medication should be under the supervision of a healthcare professional and carefully considered in pediatric patients.

*As outlined in Mark Sloan's book, The Ultimate Guide to Methylene Blue

**These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Information provided by this website or this company is not a substitute for individual medical advice. | ©BioLight, Inc, 2023

BioBlue (SR) is the very first supplement of its kind, consisting of a 50/50 blend of methylene blue and leucomethylene blue that provides the best of both worlds and delivers a Sustained Release of the mitochondrial-boosting properties of these blue molecules.

Methylene blue (MB) and leucomethylene blue (leucoMB) provide similar powerful benefits to mitochondrial function, which is quickly becoming known as the foundation and root level of all health. The mitochondria produce almost all of the energy in our body and, from a bioenergetic perspective, the more energy you have per cell = the healthier and more vitality you have. In essence, mitochondrial health is our modern day Fountain of Youth.

With that being said, MB and leucoMB have their own distinct advantages from one another. For one, methylene blue is a much darker pigment (see the picture  below demonstrating the drastic color differences of their respective powders) that lends itself to more powerful photodynamic benefits when utilized in combination with red light therapy. It is also much more fiscally friendly compared to leucoMB. However, MB takes longer to contribute its benefits, as it has to be endogenously broken down and reduced into leucoMB before it can be readily utilized. Some research indicates that peak plasma concentrations of MB are around 1.5 - 2 hours post-ingestion.

On the other hand, leucoMB has its own set of benefits. For one, since it is the reduced version of MB, it does not have to go through any internal processes in the body and is instantly bioavailable and ready to work as the powerful antioxidant it is. Also, since it is a reduced version of MB, it has even more electrons to donate (meaning it is an even more powerful antioxidant when compared to MB). The only downsides of leucoMB are that it does not provide the same photodynamic benefits as MB, given that it is not as dark of a pigment, and it is more costly.

BioBlue (SR) provides a beautiful 50/50 blend of MB and leucoMB so you get a combination of the instantaneous high-octane benefits of leucoMB and the more 'delayed' benefits of MB as it is broken down in your body and, thus, providing a sustained release mitochondrial-boosting blue molecules!

Top 10 benefits of methylene blue and leucomethylene blue*:

1. Boosting brain health/cognition

2. Anti-malarial

3. Anti-viral

4. Reduce depression

5. Mitigate/reverse dementia

6. Autism

7. Pain relief

8. Heart health

9. Cancer

10. Chemical poisoning and overdose

Learn more about methylene blue by clicking here