Adult Supplements

Methylene blue is quickly becoming a prized supplement in the health, wellness, longevity and biohacking worlds due to its many health benefits, highlighted by boosting both mitochondrial function and brain health.

To make matters even more advantageous, methylene blue possesses photodynamic capacity that makes it a major synergist with photobiomodulaton; essentially, methylene blue amplifies the benefits of red light therapy.

Ultimately, BioBlue is a supreme methylene blue product that works as a standalone cellular energizer via boosting mitochondrial health or as an incredibly powerful red light therapy synergist that can be added to any RLT treatment. This is because of the unique blend of ingredients that have been incorporated with the pharmaceutical grade (USP >99.5%) methylene blue at 1% solution.

Top 10 benefits of methylene blue*:

1. Boosting brain health/cognition

2. Anti-malarial

3. Anti-viral

4. Reduce depression

5. Mitigate/reverse dementia

6. Autism

7. Pain relief

8. Heart health

9. Cancer

10. Chemical poisoning and overdose

Learn more about methylene blue by clicking here

BioBlue ingredients:

Triple distilled biophotonic structured water - not only is the water we utilize clean, purified and distilled, but its energy has been enhanced via direct sunlight in Miron violetglass jars and has been structured, which further upgrades its energy and helps better absorb nutrients.

Methylene blue USP Grade (>99.5%), 1% solution, cGMP manufactured - only the most pure and highest-quality pharmaceutical grade methylene blue is used in BioBlue. Here are a list of some of the health benefits of methylene blue:

• Anti-viral, anti-malarial

• Major brain-boosting properties

• Reduce anxiety, depression, dementia

• Improve overall brain function, cognition, energy, attention/focus and emotional regulation

• Restores mitochondrial health and function by improving oxidative metabolism

• Selectively targets cells that need the most healing first before others

• Cancer cells are targeted first due to their inefficient energy production (which is what methylene blue targets first)

Nicotinamide mononucleotide (NMN) - highly touted by Dr. David Sinclair in his New York Times bestseller, Lifespan, this molecule is a NAD+ precursor that has become wildly popular due to its ability to increase energy and boost mitochondrial health. As we age, our NAD+ levels naturally decline and, thus, NMN can play a vital role in mitigating that decline in energy production in the mitochondria.

Colloidal gold - Produced by electrolysis that insures highest quality, homogeneity and stability. This method results in a high-quality and well-dispersed colloidal gold product with the highest zeta potential (a high zeta potential indicates that the particles have a strong electrical charge). On top of improving cognitive function, colloidal gold offers additional benefits, such as reducing inflammation, boosting the immune system, reducing aging and improving skin and hair health.

Colloidal silver - notorious for its anti-microbial properties and commonly used for wound care and skin health, colloidal silver also provides anti-inflammatory benefits, strong immune support and has some potential for respiratory support.

Fulvic acid -  known to raise the voltage of your cells, we added the purest fulvic acid in order to enhance the absorption of the ingredients. This means that the methylene blue and NMN may be taken up and better utilized by your cells and tissues. Fulvic acid has other beneficial properties, such as being a powerful antioxidant, anti-inflammatory and promotes improved gut and skin health.

BioBlue is packaged in a Miron violetglass. Miron glass elevates the frequency of enclosed water and nutrients by selectively harnessing beneficial sunlight wavelengths, enhancing their bioavailability and vitality for a more profound and resonant impact on the body.

Recommended Dosing**:

Contraindications & Precautions for Methylene Blue

Contraindications:

1. G6PD Deficiency: Methylene blue is contraindicated in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency, a genetic enzyme disorder. Using methylene blue in individuals with this condition can lead to hemolytic anemia, a potentially severe breakdown of red blood cells.

2. Sulfite Sensitivity: Some methylene blue formulations may contain sulfites, which can trigger allergic reactions in individuals with sulfite sensitivity or allergies.

Precautions:

1. Renal Impairment: Patients with kidney disease or impaired renal function should be monitored carefully when using methylene blue. Dosing adjustments may be necessary due to changes in drug elimination.

2. Hepatic Impairment: Individuals with liver disease or impaired liver function should also be monitored closely, as methylene blue is metabolized by the liver.

3. Pregnancy and Breastfeeding: The safety of methylene blue during pregnancy and breastfeeding is not well established. It should be used with caution in pregnant or nursing women, with careful consideration of the potential risks and benefits.

4. Hypotension: Methylene blue can lower blood pressure. Patients with hypotension (low blood pressure) should be monitored closely, and adjustments to the dosage may be needed.

5. Medication Interactions: Methylene blue may interact with various medications, including serotonergic agents (e.g., certain antidepressants) and monoamine oxidase inhibitors (MAOIs). These interactions can lead to potentially dangerous serotonin syndrome. Inform your healthcare provider about all medications you are taking.

6. Allergies: Individuals with known allergies to methylene blue or other dyes should avoid its use.

7. Oxidative Stress: Methylene blue has antioxidant properties. In conditions where oxidative stress is not a factor, such as in some cancers, its use may not be advisable.

8. Children: While methylene blue is generally considered safe for children when used as a dye for diagnostic purposes, its use as a medication should be under the supervision of a healthcare professional and carefully considered in pediatric patients.

*As outlined in Mark Sloan's book, The Ultimate Guide to Methylene Blue

**These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Information provided by this website or this company is not a substitute for individual medical advice. | ©BioLight, Inc, 2023

BioBlue Leuco Capsules are the first encapsulated methylene blue supplement on the market!

With BioBlue Leuco Capsules, you no longer have to worry about stained teeth/tongue, clothes, countertops, luggage bags, etc. Not a fan of the "flavor" of leucomethylene blue? That is now a memory of the past!

This supplement combines two of the most potent molecules to safely and effectively boost mitochondrial function: leucomethylene blue and taurine. Learn about the profound benefits of both ingredients below.

Methylene blue is quickly becoming a popular supplement in the wellness, longevity and mitochondrial-centric audiences. The lesser known molecule, leucomethylene blue (leucoMB), seems to have some advantages over methylene blue (MB). For starters, leucoMB is the reduced and stabilized form of MB, meaning it has gained an electron and is much more efficient for our bodies to process. When ingesting MB, your body converts into leucoMB; therefore, by ingesting leucoMB you circumvent this metabolic process. This provides the following advantages to leucoMB:

• Higher bioabsorption = increased bioavailability

• Quicker cognitive & antioxidant effect

• With MB already being an electron donor, leucoMB has even more electrons to donate; more electrons equals more energy production in the mitochondria! 

• Easier for the body to process; this is particularly important for those with liver and/or kidney issues. (LeucoMB can work where MB cannot because the body cannot process the MB and convert it to leucoMB internally)

• Lower toxicity (even ultra pure, pharmaceutical compounds, when reduced, will further remove any metals, impurities that may be left; this is an inherent result of reducing anything)

Neurofilament light chain (NfL) is an established biomarker for brain neurodegeneration. Increased concentrations NfL are known to correlate with tau pathology, disease severity, and therefore cognitive decline and brain atrophy in Alzheimer's disease. A recently published study demonstrated that taking 16 mg/day of leucoMB reduced NfL concentration in blood by 93%! 

BioBlue Leuco Capsules ingredients

• Enhancement of ATP Production - Methylene blue serves as an alternative electron carrier in the mitochondrial electron transport chain (ETC). It can bypass dysfunctional components in the ETC and facilitate electron flow, which increases ATP (energy) production, especially in cells with impaired mitochondrial function.

• Reduction of Reactive Oxygen Species (ROS) - Methylene blue has antioxidant properties and can reduce the production of reactive oxygen species (ROS) in mitochondria. Excessive ROS production can damage mitochondrial DNA, lipids, and proteins, leading to cellular dysfunction. MB helps minimize oxidative stress by acting as an electron acceptor.

• Prevention of Mitochondrial Dysfunction - By improving the efficiency of the electron transport chain and reducing oxidative stress, methylene blue helps prevent mitochondrial dysfunction. This is important for maintaining cellular energy levels, especially in tissues with high energy demands like the brain and heart.

• Protection Against Mitochondrial Damage - Methylene blue helps protect mitochondria from damage caused by toxins, ischemia (restricted blood flow), and metabolic stress. This is particularly useful in conditions that compromise mitochondrial integrity and function, such as neurodegenerative diseases and aging.

• Improved Cellular Respiration - By facilitating electron transport and improving the efficiency of the respiratory chain, methylene blue can enhance cellular respiration. This increases oxygen consumption in the mitochondria, which supports better metabolic performance and energy utilization.

• Neuroprotective Effects - Methylene blue has demonstrated neuroprotective effects, in part by improving mitochondrial function in neurons. It is being studied for potential benefits in treating neurodegenerative conditions like Alzheimer’s and Parkinson’s diseases, where mitochondrial dysfunction plays a role in disease progression.

• Protection Against Mitochondrial Permeability Transition - Methylene blue can help prevent the opening of the mitochondrial permeability transition pore (mPTP), a channel whose opening leads to mitochondrial swelling, dysfunction, and cell death. By inhibiting mPTP, methylene blue supports the longevity and resilience of mitochondria under stress.

• Promotion of Mitophagy - Methylene blue may also stimulate mitophagy, the process by which damaged or dysfunctional mitochondria are selectively removed. This helps maintain a healthy population of mitochondria within cells, promoting overall cellular vitality and function.

Learn more about methylene blue by clicking here

Taurine

• Prevention of Mitochondrial Dysfunction - Taurine can help prevent mitochondrial dysfunction by reducing oxidative damage, maintaining proper ion balance, and enhancing energy production. Mitochondrial dysfunction is linked to a range of diseases, including neurodegenerative diseases, diabetes, and heart conditions.

• Antioxidant Properties - Taurine acts as a potent antioxidant, reducing oxidative stress in mitochondria. This is important because mitochondria produce reactive oxygen species (ROS) as by-products of energy production, which can damage cells if not properly managed.

• Regulation of Calcium Homeostasis - Taurine helps regulate calcium levels within cells and mitochondria. Proper calcium balance is essential for mitochondrial function, as calcium overload can lead to mitochondrial dysfunction, energy failure, and cell death.

• Improved ATP Production - Taurine enhances mitochondrial efficiency in producing ATP (adenosine triphosphate), the main energy currency of the cell. This is vital for sustaining energy-demanding processes throughout the body, especially in tissues with high energy needs like muscles and the brain.

• Mitochondrial Membrane Stabilization - Taurine contributes to the stability and integrity of the mitochondrial membrane, which is crucial for maintaining the electrochemical gradients needed for ATP synthesis. It also protects against mitochondrial permeability transition, a process that can lead to cell death.

• Anti-Inflammatory Effects - Taurine helps reduce inflammation, which is important for protecting mitochondria from inflammatory damage. Chronic inflammation can impair mitochondrial function and contribute to diseases like cardiovascular and metabolic disorders.

Contraindications & Precautions for Methylene Blue

Contraindications:

1. G6PD Deficiency: Methylene blue is contraindicated in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency, a genetic enzyme disorder. Using methylene blue in individuals with this condition can lead to hemolytic anemia, a potentially severe breakdown of red blood cells.

2. Sulfite Sensitivity: Some methylene blue formulations may contain sulfites, which can trigger allergic reactions in individuals with sulfite sensitivity or allergies.

Precautions:

1. Renal Impairment: Patients with kidney disease or impaired renal function should be monitored carefully when using methylene blue. Dosing adjustments may be necessary due to changes in drug elimination.

2. Hepatic Impairment: Individuals with liver disease or impaired liver function should also be monitored closely, as methylene blue is metabolized by the liver.

3. Pregnancy and Breastfeeding: The safety of methylene blue during pregnancy and breastfeeding is not well established. It should be used with caution in pregnant or nursing women, with careful consideration of the potential risks and benefits.

4. Hypotension: Methylene blue can lower blood pressure. Patients with hypotension (low blood pressure) should be monitored closely, and adjustments to the dosage may be needed.

5. Medication Interactions: Methylene blue may interact with various medications, including serotonergic agents (e.g., certain antidepressants) and monoamine oxidase inhibitors (MAOIs). These interactions can lead to potentially dangerous serotonin syndrome. Inform your healthcare provider about all medications you are taking.

6. Allergies: Individuals with known allergies to methylene blue or other dyes should avoid its use.

7. Oxidative Stress: Methylene blue has antioxidant properties. In conditions where oxidative stress is not a factor, such as in some cancers, its use may not be advisable.

8. Children: While methylene blue is generally considered safe for children when used as a dye for diagnostic purposes, its use as a medication should be under the supervision of a healthcare professional and carefully considered in pediatric patients.

**These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Information provided by this website or this company is not a substitute for individual medical advice. | ©BioLight, Inc, 2023

BioBlue Capsules are the first encapsulated methylene blue supplement on the market!

With BioBlue Capsules, you no longer have to worry about stained teeth/tongue, clothes, countertops, luggage bags, etc. Not a fan of the "flavor" of methylene blue? That is now a memory of the past!

This supplement combines two of the most potent molecules to safely and effectively boost mitochondrial function: methylene blue and taurine. Learn about the profound benefits of both ingredients below.

BioBlue Capsules ingredients

• Enhancement of ATP Production - Methylene blue serves as an alternative electron carrier in the mitochondrial electron transport chain (ETC). It can bypass dysfunctional components in the ETC and facilitate electron flow, which increases ATP (energy) production, especially in cells with impaired mitochondrial function.

• Reduction of Reactive Oxygen Species (ROS) - Methylene blue has antioxidant properties and can reduce the production of reactive oxygen species (ROS) in mitochondria. Excessive ROS production can damage mitochondrial DNA, lipids, and proteins, leading to cellular dysfunction. MB helps minimize oxidative stress by acting as an electron acceptor.

• Prevention of Mitochondrial Dysfunction - By improving the efficiency of the electron transport chain and reducing oxidative stress, methylene blue helps prevent mitochondrial dysfunction. This is important for maintaining cellular energy levels, especially in tissues with high energy demands like the brain and heart.

• Protection Against Mitochondrial Damage - Methylene blue helps protect mitochondria from damage caused by toxins, ischemia (restricted blood flow), and metabolic stress. This is particularly useful in conditions that compromise mitochondrial integrity and function, such as neurodegenerative diseases and aging.

• Improved Cellular Respiration - By facilitating electron transport and improving the efficiency of the respiratory chain, methylene blue can enhance cellular respiration. This increases oxygen consumption in the mitochondria, which supports better metabolic performance and energy utilization.

• Neuroprotective Effects - Methylene blue has demonstrated neuroprotective effects, in part by improving mitochondrial function in neurons. It is being studied for potential benefits in treating neurodegenerative conditions like Alzheimer’s and Parkinson’s diseases, where mitochondrial dysfunction plays a role in disease progression.

• Protection Against Mitochondrial Permeability Transition - Methylene blue can help prevent the opening of the mitochondrial permeability transition pore (mPTP), a channel whose opening leads to mitochondrial swelling, dysfunction, and cell death. By inhibiting mPTP, methylene blue supports the longevity and resilience of mitochondria under stress.

• Promotion of Mitophagy - Methylene blue may also stimulate mitophagy, the process by which damaged or dysfunctional mitochondria are selectively removed. This helps maintain a healthy population of mitochondria within cells, promoting overall cellular vitality and function.

Learn more about methylene blue by clicking here

Taurine

• Prevention of Mitochondrial Dysfunction - Taurine can help prevent mitochondrial dysfunction by reducing oxidative damage, maintaining proper ion balance, and enhancing energy production. Mitochondrial dysfunction is linked to a range of diseases, including neurodegenerative diseases, diabetes, and heart conditions.

• Antioxidant Properties - Taurine acts as a potent antioxidant, reducing oxidative stress in mitochondria. This is important because mitochondria produce reactive oxygen species (ROS) as by-products of energy production, which can damage cells if not properly managed.

• Regulation of Calcium Homeostasis - Taurine helps regulate calcium levels within cells and mitochondria. Proper calcium balance is essential for mitochondrial function, as calcium overload can lead to mitochondrial dysfunction, energy failure, and cell death.

• Improved ATP Production - Taurine enhances mitochondrial efficiency in producing ATP (adenosine triphosphate), the main energy currency of the cell. This is vital for sustaining energy-demanding processes throughout the body, especially in tissues with high energy needs like muscles and the brain.

• Mitochondrial Membrane Stabilization - Taurine contributes to the stability and integrity of the mitochondrial membrane, which is crucial for maintaining the electrochemical gradients needed for ATP synthesis. It also protects against mitochondrial permeability transition, a process that can lead to cell death.

• Anti-Inflammatory Effects - Taurine helps reduce inflammation, which is important for protecting mitochondria from inflammatory damage. Chronic inflammation can impair mitochondrial function and contribute to diseases like cardiovascular and metabolic disorders.

Contraindications & Precautions for Methylene Blue

Contraindications:

1. G6PD Deficiency: Methylene blue is contraindicated in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency, a genetic enzyme disorder. Using methylene blue in individuals with this condition can lead to hemolytic anemia, a potentially severe breakdown of red blood cells.

2. Sulfite Sensitivity: Some methylene blue formulations may contain sulfites, which can trigger allergic reactions in individuals with sulfite sensitivity or allergies.

Precautions:

1. Renal Impairment: Patients with kidney disease or impaired renal function should be monitored carefully when using methylene blue. Dosing adjustments may be necessary due to changes in drug elimination.

2. Hepatic Impairment: Individuals with liver disease or impaired liver function should also be monitored closely, as methylene blue is metabolized by the liver.

3. Pregnancy and Breastfeeding: The safety of methylene blue during pregnancy and breastfeeding is not well established. It should be used with caution in pregnant or nursing women, with careful consideration of the potential risks and benefits.

4. Hypotension: Methylene blue can lower blood pressure. Patients with hypotension (low blood pressure) should be monitored closely, and adjustments to the dosage may be needed.

5. Medication Interactions: Methylene blue may interact with various medications, including serotonergic agents (e.g., certain antidepressants) and monoamine oxidase inhibitors (MAOIs). These interactions can lead to potentially dangerous serotonin syndrome. Inform your healthcare provider about all medications you are taking.

6. Allergies: Individuals with known allergies to methylene blue or other dyes should avoid its use.

7. Oxidative Stress: Methylene blue has antioxidant properties. In conditions where oxidative stress is not a factor, such as in some cancers, its use may not be advisable.

8. Children: While methylene blue is generally considered safe for children when used as a dye for diagnostic purposes, its use as a medication should be under the supervision of a healthcare professional and carefully considered in pediatric patients.

**These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Information provided by this website or this company is not a substitute for individual medical advice. | ©BioLight, Inc, 2023

Methylene blue is quickly becoming a highly sought after supplement in the health, wellness, longevity and biohacking worlds due to its many health benefits, highlighted by boosting both mitochondrial function and brain health.

BioBlue Calm is a blend of six herbs and minerals combined with pharmaceutical grade methylene blue (USP >99.5%) to help promote relaxation and a sense of calm. This recipe includes all of the same ingredients as our flagship BioBlue product minus nicotinamide mononucleotide (NMN). We decided to remove NMN because while is not a stimulant, it can be stimulating to our physiology given its properties for improving mitochondrial function and energy production.

Between the removal of the NMN and the addition of:

• Ashwagandha

• Valerian

• Passionflower

• Kava

• Magnesium glycinate

• Magnesium L-threonate

...BioBlue Calm functions as a "weighted blanket" for your brain and your nervous system, providing a physiological tranquility in times of stress, anxiety and/or when falling asleep is difficult.

All of the above herbs and minerals contribute to reducing cortisol levels and improved GABA activity in the brain. This alone promotes a deep sense of calm.

Top 10 benefits of methylene blue*:

1. Boosting brain health/cognition

2. Anti-malarial

3. Anti-viral

4. Reduce depression

5. Mitigate/reverse dementia

6. Autism

7. Pain relief

8. Heart health

9. Cancer

10. Chemical poisoning and overdose

Learn more about methylene blue by clicking here

BioBlue Calm ingredients:

Triple distilled biophotonic structured water - not only is the water we utilize clean, purified and distilled, but its energy has been enhanced via direct sunlight in Miron violetglass jars and has been structured, which further upgrades its energy and helps better absorb nutrients.

Methylene blue USP Grade (>99.5%), 1% solution, cGMP manufactured - only the most pure and highest-quality pharmaceutical grade methylene blue is used in BioBlue. Here are a list of some of the health benefits of methylene blue:

• Anti-viral, anti-malarial

• Major brain-boosting properties

• Reduce anxiety, depression, dementia

• Improve overall brain function, cognition, energy, attention/focus and emotional regulation

• Restores mitochondrial health and function by improving oxidative metabolism

• Selectively targets cells that need the most healing first before others

• Cancer cells are targeted first due to their inefficient energy production (which is what methylene blue targets first)

Ashwaganda root (Withania somnifera)* - Ashwagandha is an adaptogenic herb that has been used for centuries in traditional Ayurvedic medicine to promote relaxation, reduce stress, and improve overall well-being. Ashwagandha helps promote calmness by reducing cortisol levels, enhancing GABA activity in the brain, reducing inflammation and contributing as an antioxidant and neuroprotection. 

Valerian rhizome w/ root (Valeriana officinalis)* - Valerian root has been used for centuries as a natural remedy for promoting relaxation and improving sleep. Valerian helps promote calmness by enhancing GABA activity in the brain, modulating serotonin receptors in the brain, modulating adenosine receptors (which promotes relaxation and sleepiness) and reducing cortisol levels.

Passionflower flowering aerial parts (Passiflora incarnata)* - Passionflower has a long history of use as a natural remedy for promoting relaxation and reducing anxiety. Passionflower helps promote calmness by enhancing GABA activity in the brain, modulating serotonin receptors in the brain, contributing as an antioxidant, reducing cortisol levels and modulating of neurotransmitters, such as dopamine and noradrenaline.

Kava rhizome w/ root (Piper methysticum) - Kava is a plant native to the South Pacific islands, where it has been used for centuries in traditional ceremonies and as a beverage with sedative and anxiolytic (anxiety-reducing) effects. The relaxation-promoting effects of kava are primarily attributed to its bioactive compounds, particularly kavalactones. Kava helps promote calmness by  enhancing GABA activity in the brain, modulating of neurotransmitters (i.e., dopamine and noradrenaline), reducing cortisol levels, relaxing muscles and promoting reduced inflammation and antioxidant activity. 

Magnesium glycinate -  is a form of magnesium that is chelated with glycine, an amino acid. This compound is often used as a dietary supplement to address magnesium deficiency, and it is also known for its calming and relaxation-promoting effects. Magnesium glycinate helps promote calmness by its improved absorption (compared to other forms of magnesium), regulation of neurotransmitters (such as GABA), modulation of the HPA axis (which helps reduce cortisol levels), relaxing muscles, regulation of the nervous system (i.e., reducing excitability), reducing inflammation and promoting restful sleep.

Magnesium L-threonate -  is a form of magnesium that is bonded with L-threonate, a compound derived from vitamin C. This specific formulation is notable for its ability to effectively penetrate the blood-brain barrier, leading to increased magnesium levels in the brain. Magnesium L-threonate helps promote calmness by enhanced GABA activity, modulation of NMDA receptors (i.e., reducing hyperactivity in the brain), protection against excitotoxicity, reducing inflammation and enhancing brain function and synaptic activity.

Colloidal gold - Produced by electrolysis that insures highest quality, homogeneity and stability. This method results in a high-quality and well-dispersed colloidal gold product with the highest zeta potential (a high zeta potential indicates that the particles have a strong electrical charge). On top of improving cognitive function, colloidal gold offers additional benefits, such as reducing inflammation, boosting the immune system, reducing aging and improving skin and hair health.

Colloidal silver - notorious for its anti-microbial properties and commonly used for wound care and skin health, colloidal silver also provides anti-inflammatory benefits, strong immune support and has some potential for respiratory support.

Fulvic acid -  known to raise the voltage of your cells, we added the purest fulvic acid in order to enhance the absorption of the ingredients. This means that the methylene blue and NMN may be taken up and better utilized by your cells and tissues. Fulvic acid has other beneficial properties, such as being a powerful antioxidant, anti-inflammatory and promotes improved gut and skin health.

* = organic ingredient

BioBlue Calm is packaged in a Miron violetglass. Miron glass elevates the frequency of enclosed water and nutrients by selectively harnessing beneficial sunlight wavelengths, enhancing their bioavailability and vitality for a more profound and resonant impact on the body.

Recommended Dosing**:

Contraindications & Precautions for Methylene Blue

Contraindications:

1. G6PD Deficiency: Methylene blue is contraindicated in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency, a genetic enzyme disorder. Using methylene blue in individuals with this condition can lead to hemolytic anemia, a potentially severe breakdown of red blood cells.

2. Sulfite Sensitivity: Some methylene blue formulations may contain sulfites, which can trigger allergic reactions in individuals with sulfite sensitivity or allergies.

Precautions:

1. Renal Impairment: Patients with kidney disease or impaired renal function should be monitored carefully when using methylene blue. Dosing adjustments may be necessary due to changes in drug elimination.

2. Hepatic Impairment: Individuals with liver disease or impaired liver function should also be monitored closely, as methylene blue is metabolized by the liver.

3. Pregnancy and Breastfeeding: The safety of methylene blue during pregnancy and breastfeeding is not well established. It should be used with caution in pregnant or nursing women, with careful consideration of the potential risks and benefits.

4. Hypotension: Methylene blue can lower blood pressure. Patients with hypotension (low blood pressure) should be monitored closely, and adjustments to the dosage may be needed.

5. Medication Interactions: Methylene blue may interact with various medications, including serotonergic agents (e.g., certain antidepressants) and monoamine oxidase inhibitors (MAOIs). These interactions can lead to potentially dangerous serotonin syndrome. Inform your healthcare provider about all medications you are taking.

6. Allergies: Individuals with known allergies to methylene blue or other dyes should avoid its use.

7. Oxidative Stress: Methylene blue has antioxidant properties. In conditions where oxidative stress is not a factor, such as in some cancers, its use may not be advisable.

8. Children: While methylene blue is generally considered safe for children when used as a dye for diagnostic purposes, its use as a medication should be under the supervision of a healthcare professional and carefully considered in pediatric patients.

*As outlined in Mark Sloan's book, The Ultimate Guide to Methylene Blue

**These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Information provided by this website or this company is not a substitute for individual medical advice. | ©BioLight, Inc, 2023

BioBlue (SR) is the very first supplement of its kind, consisting of a 50/50 blend of methylene blue and leucomethylene blue that provides the best of both worlds and delivers a Sustained Release of the mitochondrial-boosting properties of these blue molecules.

Methylene blue (MB) and leucomethylene blue (leucoMB) provide similar powerful benefits to mitochondrial function, which is quickly becoming known as the foundation and root level of all health. The mitochondria produce almost all of the energy in our body and, from a bioenergetic perspective, the more energy you have per cell = the healthier and more vitality you have. In essence, mitochondrial health is our modern day Fountain of Youth.

With that being said, MB and leucoMB have their own distinct advantages from one another. For one, methylene blue is a much darker pigment (see the picture  below demonstrating the drastic color differences of their respective powders) that lends itself to more powerful photodynamic benefits when utilized in combination with red light therapy. It is also much more fiscally friendly compared to leucoMB. However, MB takes longer to contribute its benefits, as it has to be endogenously broken down and reduced into leucoMB before it can be readily utilized. Some research indicates that peak plasma concentrations of MB are around 1.5 - 2 hours post-ingestion.

On the other hand, leucoMB has its own set of benefits. For one, since it is the reduced version of MB, it does not have to go through any internal processes in the body and is instantly bioavailable and ready to work as the powerful antioxidant it is. Also, since it is a reduced version of MB, it has even more electrons to donate (meaning it is an even more powerful antioxidant when compared to MB). The only downsides of leucoMB are that it does not provide the same photodynamic benefits as MB, given that it is not as dark of a pigment, and it is more costly.

BioBlue (SR) provides a beautiful 50/50 blend of MB and leucoMB so you get a combination of the instantaneous high-octane benefits of leucoMB and the more 'delayed' benefits of MB as it is broken down in your body and, thus, providing a sustained release mitochondrial-boosting blue molecules!

Top 10 benefits of methylene blue and leucomethylene blue*:

1. Boosting brain health/cognition

2. Anti-malarial

3. Anti-viral

4. Reduce depression

5. Mitigate/reverse dementia

6. Autism

7. Pain relief

8. Heart health

9. Cancer

10. Chemical poisoning and overdose

Learn more about methylene blue by clicking here